If you are someone that enjoys skincare, you may be protecting your skin from skin cancer if you use this unique antioxidant mask. Researchers in a paper released January 20, 2018 say that hesperidin, which has the highest concentration from the peel of the unripe citrus reticulata fruit, can protect against UV, which contributes to skin cancers like melanoma, the deadliest form of skin cancer.
The exact cause of all Melanomas isn't clear, but exposure to ultraviolet (UV) radiation from sunlight or tanning beds increases your risk of developing melanoma due to skin mutations; these mutations prompt the cells to grow abnormally and spread to other tissues in the body, where it can be fatal. But, A recent study shows that hesperidin, a flavonoid found in this anti-aging mask, can protect against skin degradation after exposure to ultraviolet B (UVB) radiation. The paper, which appeared in BMC Complementary and Alternative Medicine, also prevented UVB-induced skin thickening, wrinkle formation, and inflammation. Some bullet points of the study are:
Hesperidin is known for its antioxidant, anti-inflammatory, and immune modulatory activities. Researchers looked at whether the flavonoid was effective in preventing photoaging using hairless mice models.
The mice were divided into three groups: control, UVB-treated vehicle, and UVB-treated hesperidin. In particular, mice in the hesperidin group were given treated with water containing 100 milligrams per kilogram body weight (mg/kg) of hesperidin daily.
Results showed that mice that were treated with hesperidin had improved length and depth of wrinkles, as well as inhibited the development of skin thickness and epidermal hypertrophy.
Mice that were treated with hesperidin also exhibited decreased MMP-9 (matrix metallopeptidase 9) and pro-inflammatory cytokine expression.
Of course, we believe that these results need to be repeated and confirmed, and that it’s too early yet to know if hesperidin can protect you from skin cancer. But the findings support the idea that there might be more you can do to protect yourself from the sun’s harmful rays than only slathering your body in sunscreen.
Lee HJ, Im AR, Kim SM, Kang HS, Lee JD, Chae S. THE FLAVONOID HESPERIDIN EXERTS ANTI-PHOTOAGING EFFECT BY DOWNREGULATING MATRIX METALLOPROTEINASE (MMP)-9 EXPRESSION VIA MITOGEN ACTIVATED PROTEIN KINASE (MAPK)-DEPENDENT SIGNALING PATHWAYS. BMC Complementary and Alternative Medicine. 30 January 2018;18(39). DOI: 10.1186/s12906-017-2058-8